Coconut Oil, Ketones and Alzheimer's

Saturday, August 10, 2013

The Eating Academy - Good articles on ketosis and many other topics by Dr. Peter Attia


Here is a link to a blog by Peter Attia, MD on nutrition, stressing low carbohydrate diet with many very interesting articles on ketosis (see part I and Part II).

http://eatingacademy.com/start-here

Wednesday, August 7, 2013

Dr. Stephanie Seneff of MIT on Cholesterol, ApoE4, Statins, Beta Amyloid and Alzheimer's



Here is a link to a very thorough and highly researched article by Dr. Stephanie Seneff of MIT discussing the importance of fat and cholesterol, how they work in the brain, why statin use may be counterproductive for people at risk for and dealing with Alzheimer's, the function of beta amyloid and why a high fat diet may be beneficial.  I found this especially enlightening in its explanation of how cholesterol is packaged as it is transported throughout the body, and what it is packaged with in LDL particles, for example, may be a surprise.

http://coconutoil.com/the-clue-to-why-low-fat-diet-and-statins-may-cause-alzheimers/

Dr. Seneff has written many other similar articles of great interest to those concerned with cholesterol, statins, Alzheimer's, autism and other neurodegenerative diseases, many of which can be downloaded from her homepage.  http://people.csail.mit.edu/seneff/

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Tuesday, July 23, 2013

Fuel for Thought

Many people ask me to suggest a convenient way that does not involve cooking to provide coconut and MCT oil for their loved ones who are in assisted living, or are looking for a convenient way to take it at home, or carry along while travelling or just out and about.  One such product is called Fuel for Thought and is available directly from Cognate Nutritionals by way of  www.cognatenutritionals.com or by calling  (855) 453-8663.  The company is located in the USA in Connecticut.  In the first edition of my book, the working name of this product was Cocomul but is now called Fuel for Thought.

Steve and I have had the opportunity to try out Fuel for Thought and it is a delicious, creamy vanilla flavored liquid that is easiest taken as is but can also be mixed into other foods and liquids.  Fuel for Thought® has been scientifically designed to provide a high concentration of MCTs which are partly converted in the liver to ketones that act as alternative fuel for brain cells.  In this regard, it has been designed to support cognitive health.  The makers state this product contains NO cholesterol, gluten, transfats, soy, dairy, or fructose, is vegetarian and very low in sodium. 

The beauty of Fuel for Thought is that it is packaged in one ounce single-serving bottles that do not require refrigeration, and are  sold as a case containing 60 doses.  For someone in assisted living, rather than trying to provide food containing coconut oil or getting the staff to give the patient coconut oil, the loved one's physician could order that Fuel for Thought be provided to the patient at set times of day, with meals, for example.

The recommendation from the company is to take one bottle twice a day, beginning with a portion of the bottle initially and increasing as tolerated.  The product is designed such that the amount of ketones produced by taking one ounce is equal to three tablespoons of coconut oil but with only 100 calories, as opposed to about 360 calories from the equivalent amount of coconut oil.

The product is currently being studied in a clinical trial of Alzheimer's and coconut/MCT oil versus placebo at the Byrd Alzheimer's Institute at University of South Florida in Tampa.
It is comparable to my idea of mixing coconut oil and MCT oil to reach higher levels of ketones while retaining the many health benefits of coconut oil.  I am giving Steve this mixture several times a day to try to keep ketones available to his brain 24/7.  For that reason I am involved with the company as a scientific advisor.
 
The concept here is that MCT oil is partly converted in the liver to ketones which act in the brain as an alternative fuel to glucose. People who have insulin deficiency or insulin resistance have difficulty getting glucose, the usual primary fuel for the brain and other organs, into the cells and eventually they malfunction and diet. This product would be useful not only for people who suffer from Alzheimer’s, but also, Parkinson’s, ALS, multiple sclerosis, diabetes, Huntington’s, and most other conditions where there is insulin resistance or decreased glucose uptake into cells.

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TED x USF talk link

I have been having trouble getting by drafts to publish on my blog lately but now appear to be okay!

Here is a link to a TED talk I did in February at TEDxUSF in later February - 18 minutes long:

http://www.youtube.com/watch?v=Dvh3JhsrQ0w

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Tampa Bay Times Article - Byrd Alzheimer's Institute to study coconut oil in people with Alzheimer's!


Here is a link to the story:

http://www.tampabay.com/news/health/spring-hill-couple-inspires-research-into-coconut-oil-for-alzheimers/2124596

This story spawned a similar TV story on ABC Action News that aired in the Tampa Bay area.  I will post a link when I receive it.

Sorry I have not posted here much lately!  I have been more active on Facebook.  Just look up Mary Newport and ask to be friends.

The second edition of my book was released a couple of months ago.  There is a link to order from Amazon on my website www.coconutketones.com.



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Sunday, February 3, 2013

New Interview Series - Ketones and Alzheimer's

I had the opportunity to give an interview for Scott Peters of iHealth Tube Video while at a conference where I was speaking. Here are links to the various segments:

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Monday, January 7, 2013

New Important Article on Ketone Ester from Dr. Richard Veech NIH


A groundbreaking research study of a ketone ester in an Alzheimer's mouse model was released for publication January 4, 2012 in Neurobiology of Aging by Yoshira Kashiwaya, M.D. and others in the laboratory of Dr. Richard L. Veech at the NIH in Rockville, Maryland. This study showed that, compared to animals fed a normal control diet, the Alzheimer's model mice who were fed the ketone ester (D-beta-hydroxybutyrate-(R)-1,3-butanediol) had significantly less amyloid and tau protein that form the plaques and tangles in the Alzheimer's brain, and the animals showed reduced anxiety, and improved learning and memory compared to the mice fed the control diet.

The Alzheimer brain in people becomes resistant to insulin beginning at least ten to twenty years before symptoms appear and this affects the ability of the brain cells to use glucose causing them to malfunction and die. It was discovered in the late 1960's in the laboratory of George Cahill, M.D. (now deceased) that the brain easily switches over to using ketone bodies as an alternative fuel during starvation when glucose supplies are used up. This new research is the culmination of decades of research that followed, and, for the first time, shows that ketones could lessen the changes that occur in the brain and also improve cognitive function in this disease. In addition to acting as an alternative fuel, ketones mimic some of the effects of insulin and are also anti-inflammatory. Inflammation is another key feature affecting the Alzheimer's brain.

Toxicity studies have already been conducted of the ketone ester in people showing there are no adverse effects and it has been approved by the FDA as "Generally Regarded as Safe (GRAS)". Funding is now urgently needed to mass produce this ketone ester and conduct human clinical trials.

A copy of the entire article may be obtained on my website at the top of the first page www.coconutketones.com.

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